Isabel Alfaro is a young and talented CIA officer, starting her first day as a field agent in Mexico City (CDMX). She's smart, confident and excited. Her dreams get swiftly destroyed by her new boss, Wayne Addison, longtime CIA case officer and current Deputy Chief of Station. She quickly learns that he's on a personal vendetta to find and kill Rafael Bautista, the mysterious and brutal head of the Guerrero Cartel. Bautista, we find, is at war with the more established Northern Federation cartel, in an attempt to become the main cartel in Mexico, and seems destined to win it. Only a few hours in, Isa starts to wonder if Wayne is unhinged. He puts her life in grave danger when he takes her to one of the most dangerous spots in the city, the barrio of Tepito, in search of his unofficial source, a local gangster called El Cocodrilo or Coco for short. Meanwhile, we meet Eduardo Yzaguirre, the Mayor of Mexico City, the most inspirational politician in the country - young, vibrant, ...

After the recent bloodshed in the Zócalo, panic reigns in Mexico City. The Mexican and American forces come together in the Joint Mexican/American Drug Trafficking Fusion Center, where the elite Mexican Navy, DEA and CIA forces work hand-in-hand. Under Wayne's direction and that of the recently assigned head of Mexican Naval Intelligence, Admiral Romero, the Fusion Center tries to track Bautista's steps. However, Romero, a proud Mexican patriot, makes sure thing don't go smoothly for Wayne. Isa, now working on a lead about the financial operation of the Guerrero Cartel, ignores orders and follows her instincts to go after what she thinks is a promising lead. And Lalo engages in a political battle with the Mexican President Trueba, his long political adversary and the only man in Mexico with more power than him, to remain in control of the Zócalo case, and, in a sense, to remain in control of the city.

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