Celebrated obstetrician and gynecologist William Masters, happily married but unlike to get his wife pregnant, decides to scientifically research sexual orgasms, and 'hiring' a prostitute won't suffice. Besides his official research assistant, brilliant graduate and slick, handsome womanizer Ethan Haas, he needs a female secretarial assistant and decides to recruit informally. The university refuses to contribute to such a 'lecherous' project. Written by KGF Vissers

Although personally more amused than embarrassed during a demonstration of he sex research equipment, medical provost Barton Scully lets the board cut off all college funding when they learn about its 'explicit, adult' nature. Masters gives Virginia her notice, but finds he needs her help to transfer the experiment to the brothel, where the madam compounds outrageous demands, even a respectable hospital job. Frustrated over sexual neglect by Virginia, academic research assistant Ethan seduces a nurse, only to find her sexually narrow-minded. Libby Masters demands Ethan back as treating fertility doctor when she gets wind of the unsavory brothel observations after the commissioner saved William from raid arrest, while the venue scares off respectable participants. Written by KGF Vissers

Dr. William Masters wants to render his study statistically relevant by broadening it to an average test persons population. So men are recruited trough the brothel, but in stead of 'average'' clients they are call boys. On e of them, Dale, convinces Masters to study gays too and hands him the blackmail munition: he's the married provosts's secret lover. Dr. Ethan Haas wants out of Masters's shadow by delivering quadruplets and gets the provost's permission, but his mentor takes over. When Libby Masters despairs about the fertility treatment, Virginia breaks medical confidentiality by telling her William is the sperm count patient, but Ethan announces shortly after she's finally pregnant. Written by KGF Vissers

Ethan's frustration over having the quadruplets taken over by Masters is soothed by telling his wife she's finally pregnant, but he can't handle Virginia's hard-to-get arrogance. Virginia's penniless ex George Johnson, father of rascal Henry, invites himself to her place and, beyond hope, bed when expelled by his landlord, then joins the study as volunteer under an alias, which she spills to Masters. Wiliam is far from amused that his wife invited his widowed mother Estabrooks Masters and invites his colleagues to a party in her honor, and worse: she wants to move into St.Louis. Written by KGF Vissers

Dr. Ethan Haas's frustration grows as his date Vivian Scully, the provost's daughter, seduces him 'no ties' but turns out a virgin and eager to tie him up as 'perfect match'. Dr. Austin Langham's initial joy to be asked back for the sex study turns into horror when he learns it's now about non-lovers and experiences erectile dysfunction, a first. Her son Henry misses his father, bitterly scolds her near-permanent absence and wants to move,ignoring George never even wanted offspring. William shows little emotion when wife Libby's hope is crushed by a stillbirth. Written by KGF Vissers

Provost Scully fails to make call boy Dale admit he spilled the beans on their affair. Ethan feels trapped by Vivian but dares not provoke her father. Frustrated over his erectile 'failure', chronically sleepless Austin starts an affair with the provost's wife, Margaret Scully. A week in Florida fails to appease Libby, who sends William back home as he only had eyes and ears for senior room neighbors with a surprisingly vivid sex life. Back home, Virginia convinces him also to examine the love-factor. Written by KGF Vissers

Dale bravely rescues 'regular client' Barton from physical abuse by brutish gay bashers. Ethan dares not fail the provost's daughter expectation to go steady and exclusive and resumes Libby's fertility treatment, which William called futile, and proves successful again. Feeling frustrated and lonely, Austin re-finds his libido in an affair with the provost's adulterating wife Margaret Scully. William and Virginia join their own test subjects list, pretending it's just scientific research, while proving the psychosomatic effect of unquantifiable emotional components in a relationship. Written by KGF Vissers

Dale walks off, deeply hurt, when closet gay client Barton, whose wife demands a divorce given their mutual adultery, offers to pay him for 'aversion therapy'. Vivian eagerly jumps on Ethan before he can even formally propose to her. The study is expanded to psychosomatic interaction and the theory of two unequal types of female orgasm by adding to the team a nerdy engineer who devised a camera, suitable to film within that organ during stimulation. Written by KGF Vissers

When Vivian discovers that Ethan is a Jew, albeit 'non-practicing', she gets him to agree to convert to catholicism so she can have her church wedding, but he realizes he can't give up his entire identity for a woman he doesn't even really love and cancels the marriage. Libby is grateful to Ethan for resuming her fertility treatment, but when the initially secret pregnancy comes to William's ears, he's furious at both. The sex study becomes ever bolder, involving both 'researchers' ever more physically, yet she refuses to be paid like other subjects, while even their eager secretary changes her mind about being filmed. Written by KGF Vissers

Ethan feared to lose his university position due to his broken-off engagement with the provost's daughter, but it's Masters who reports him 'incompetent' as revenge for his wife's clandestine, however successful fertility treatment. William is shocked even worse when Vurginia's loyalty is not to him and the scientific protocol but to a pregnant voluntary test subject, betraying confidential data to her and the presumed father, Dr. Austin Langham, who desperately needs the protection of the contractual anonymity guarantee. Furthermore, she teams up with research funds rival DePaul. Written by KGF Vissers

Ethan, already the kids' favorite visitor by far, sweetly volunteers to 'babysit' while Virgina and DePaul attend a medical convention, which they miss anyway because their bus arrived too late. Their father rivals for their affection, but soon realizes Ethan would make an ideal stepfather. Having fired Virginia as assistant, Masters must prepare his research results presentation with near-clueless Libby, a recipe for disaster, and decides to 'spice up' the material. Lilian and Virginia, now her assistant in the breast cancer project, don't even male it to an out of state medical convention, but get inspired to propagate the simple test alternatively. Written by KGF Vissers

Dr. Masters' big day is at hand after 12 months of studies. Without Virginia as a voice of moderation will Bill's pitch hit the mark? Margaret Scully is confronted with her husbands homosexuality and investigates what is involved with his 'treatment'. Dr. Austin Langham has a job offer from L.A and the climax to the episode sees Virginia Johnson reading the notes from Dr. William Masters presentation at home in the rain, to hear a knock at the door. Written by Stewart from Brisbane.