The vampire brothers Damon and Stefan Salvatore, eternal adolescents, having been leading normal lives, hiding their bloodthirsty condition, for centuries, moving on before their non-aging is noticed. They are back in the Virginia town where they became vampires. Stefan is noble, denying himself blood to avoid killing, and tries to control his evil brother Damon, who promised to Stefan an eternity of misery. Stefan falls in love with schoolgirl Elena, who has an uncanny resemblance to the Salvatore brothers old love, Katherine; and whose best friend Bonnie is a witch. Written by KGF Vissers

Months after Damon and Enzo mysteriously vanished from the Armory vault, Stefan tirelessly pushes forward with their search, while Bonnie struggles holding onto hope that they will be found. Meanwhile, a dangerous encounter with an unexpected visitor leaves Caroline and Alaric fearing that someone - or something - may be targeting their family. Finally, after following some mysterious clues, Stefan realizes that whatever has a hold of his brother may have a more damaging grip over him than he could have ever imagined. Written by Raul Alexandru

After learning someone from Stefan's past might be Damon and Enzo's next target, Stefan, Bonnie and Caroline head to North Carolina. While there, Bonnie takes drastic measures in an attempt to break Enzo free of whatever has a hold over him.

As Enzo continues to fight the control over him, Bonnie finds herself at the center of a deadly game and forced to make a heart wrenching decision involving two of the most important people in her life. At the Armory, Alaric researches a mysterious artifact that he hopes will help in their fight to get Damon and Enzo back. Finally, Damon's downward spiral leads him to Tyler Lockwood who attempts to talk some sense into him before it's too late.

Meanwhile Alaric and Stefan try to find out about the origins of what they are up to, Damon is searching for an artifact so he travels to Texas where he encounters Peter Maxwell who leads him to a new revelation.

Stefan and the others remember what matters most when tragedy strikes close to home.

When her children become the focus of the Siren's latest plan, Caroline (Candice King) takes drastic measures to ensure nothing gets in the way of keeping her family safe. In a race against the clock, Stefan (Paul Wesley) pledges to do everything he can to save the twins, while tensions between Alaric (Matt Davis) and Caroline boil over, leading them to face some harsh realities about the future of their family. Meanwhile, when Enzo (Michael Malarkey) finds himself unable to fight off Sybil's (guest star Nathalie Kelley) latest move, Stefan dives into his subconscious and along the way, sets off a chain of events that leaves him faced with a life-changing decision.

Faced with the fallout from his interaction with Cade (guest star Wole Parks), Stefan (Paul Wesley) is determined to have one thing go right - Christmas Eve with Caroline. However, when Damon (Ian Somerhalder) and Sybil (guest star Nathalie Kelley) crash their Christmas Eve dinner, which had been joined by Alaric (Matt Davis), Matt (Zach Roerig) and Peter (guest star Joel Gretsch), things quickly take a dark and twisted turn. Meanwhile, in a series of flashbacks to Stefan's past, Cade's attempt to entice him with his mysterious agenda leaves Stefan faced with an unimaginable decision. Kat Graham and Michael Malarkey also star.

Stefan and Damon attend an anger management support group looking for their next victim. Sybil is still alive and teaching a group of high school students who she'll later use as leverage to get Caroline to locate a historical artifact that can be used against her. Meanwhile, Stefan and Damon continue their commitment to Cade as they test the morals of a young doctor, Tara.

Stefan and Damon return to Mystic Falls at Sybil's request as she is still in search of the historical artifact. Bonnie returns from Paris wearing a vial of Enzo's blood making Caroline wonder if she will become a vampire. Stefan, Damon, Caroline, Bonnie and Enzo all attend the Miss Mystic Falls pageant, where Sybil continues to taunt Damon with memories of Elena.

Sybill puts Damon in a catatonic state for revenge. Caroline and Bonnie enter Damon's mind and realize Stefan is the key to his fate. Sybill competes with her sister for control of the bell.

Cade returns to Mystic Falls with new assignments for Damon and Stefan that each lead to unthinkable consequences.

In order to save Stefan's soul, Damon makes a deal with Cade to retrieve the Maxwell journal. Alaric and Matt refuse to hand the journal over as it may contain the key to destroy Cade. Caroline is trying desperately to connect with Stefan before Cade goes through with his plan Written by Seif Capo

Damon and Alaric come face to face with an old enemy after they obtain a weapon that may be able to destroy Cade. Stefan is held captive by a surprising acquaintance and is forced to confront a dark secret from his past. Meanwhile, Caroline and Matt try to keep Stefan's violent history from destroying him. Cade focuses his attention on Bonnie and digs deep into her mind Written by Toby Padilla

Damon and Stefan join forces against Cade to protect Elena's casket, while Caroline and Alaric cope with their daughters' growing powers.

A wedding is quickly planned in order for Damon and Stefan to lure a dangerous enemy out into the open.

With the fate of Mystic Falls at stake, Stefan and Damon must fight their greatest enemy for one last battle.