Macarena is a finance worker who is put in prison while she is in a romance with the company chief. She has to adapt to her new life in prison Cruz del Sur. She has to be careful because of the other prisoners. The prison officials have to solve an issue inside.

Life in prison is more complicated now that Macarena knows how to live in. She tells her parents why she is accused. Her father tries to solve the problem outside to help Macarena.

Macarena discovers a new tip to find the 9 million Yolanda buried before she was arrested. Macarena's father and brother hire a new attorney to help her. She has new friends inside the prison. While, the prison officials are under lot of pressure.

A prison official is accused by one woman inside. Macarena's father ask for help to an old workmate. The Egyptian is following Leopoldo and Román. One of the women is under pressure to help with the police investigation.

Macarena gets a new cellmate and they become great friends. Prison guard Palacios is wrongly accused of sexual impropriety and suspended. Macarena's brother Roman is kidnapped by Zulema's boyfriend.

Prison guard Fabio gets Palacios off the hook. Macarena is caught on tape admitting to possessing the SIM card. The police take Macarena to the forest to find the missing money, but they're not alone.

Macarena has changed her mind about her pregnancy and is happy to be expecting a baby boy. The warden delivers some good news. Zulema is growing increasingly worried about her boyfriend's silence.

Zulema's boyfriend sneaks into Macarena's family home and steals the photos showing the secret location of the stolen millions. Fabio informs Macarena about a betrayal. Zulema gets a secret message.

Macarena's caught smuggling drugs and ends up in debt to the prison doctor, Zulema and her rival Anabel. As Zulema prepares to escape, Leopoldo closes in on her boyfriend and is ready to confront him.

A DNA test could help to prove Macarena's innocence, but the doctor refuses to perform one at this stage in her pregnancy. Macarena asks Fabio to help her, but things don't go as she had planned.

Following Fabio's disappearance Macarena gets an emergency hearing. However she uncovers Zumela's plan.

Roman is forced to confess everything to his mother, who removes a bullet from the leg of Zulema's boyfriend. Macarena gets into big trouble with the other inmates when a fight results in a broken TV.

Zulema poisons and kidnaps Macarena and also takes Palacios hostage. She insists that unless Leopoldo releases her boyfriend right away, Macarena will lose the baby, but Leopoldo has his own plan.

Macarena is out of the infirmary but the prison doctor wants to transfer her to a psychiatric hospital against her will. Macarena's family has the stolen money but Zulema's boyfriend is after them.

When Zulema's boyfriend takes revenge on Roman's family, Macarena attacks Zulema. Fabio's suspicions are confirmed. DNA samples taken at the time of Macarena's miscarriage prove her ex was lying.

Zulema betrays her boyfriend for money. Roman resolutely seeks revenge. Macarena is about to attend a court hearing that could secure her freedom when she stumbles upon Zulema's latest escape plan.