Season 2 picks up where Season 1 left off, moments after the launch of the tactical nuclear weapons triggered by Murphy. It's every man for him/herself. Our Heroes split up as they try to outrun the impending blast. Citizen Z finds himself battling thawed zombies and unable to communicate with the team. In a desperate attempt to help them out on their quest to get to California and the CDC, Citizen Z issues an on air bounty for Murphy. Suddenly everyone wants a piece of the Murphy, including a mysterious and deadly bounty hunter, Vasquez.

Following Citizen Z's on-air bounty announcement, it seems like everyone left who isn't a zombie is on the hunt for Murphy -- and they're not afraid to do whatever it takes to bring him in dead or alive! Newly reunited, our Heroes find themselves battling both zombies and over-eager bounty hunters. The fighting is fierce, resulting in a near-death experience for each of our Heroes, culminating in a tragedy no one saw coming. In all the confusion, Murphy manages to give our Heroes the slip yet again. Vasquez, at first interested only in bagging Murphy for himself, starts to see the value in working with our Heroes rather than against them. Together they must work as a team to figure out just where Murphy has gone now.

Our Heroes manage to finally track Murphy down. They come across a wagon train caravan of desperate survivors transporting victims of the nuclear blast to safety. Along the way they are attacked by Blasters, superfast zombies mutated by the radioactive fallout. Our Heroes are introduced to Z-Weed, an ultra-potent strain of marijuana grown in zombie compost. They go on a quest for Batch 47, a potential cure for the Zombie Virus.

Murphy and Cassandra head to the laboratory in Minnesota and they find a group of people desperate to get the herbal cure against the zombie virus Batch 47. However the greenhouse with Batch 47 is under siege of a hybrid type of zombies entwined with plant. The researcher of Batch 47 is Odegard, who is using zombie heads in his experiment. When the survivors arrive in the spot, they decide to collect the seeds to help a girl that is sick. Murphy stumbles with Dr. Kurian and stays with him. Meanwhile the drug lord Escorpion arrives with his gang and subdue the survivors. Then he uses a great dose of Batch 47 in Odegard, killing him. What will happen to the possible herb cure? Written by Claudio Carvalho, Rio de Janeiro, Brazil

Serena is near to deliver her baby and the group decides to take her to a nearby Mennonite community. When they arrive, 10k, Addy and Doc kill zombies and are sprayed with anthrax. Soon 10k and Addy are sick, but Doc is not affected since he had taken vaccines against many diseases when he served the army. Meanwhile Serena delivers her baby while Warren takes a decision to cure 10k and Addy. Written by Claudio Carvalho, Rio de Janeiro, Brazil

Warren, Addy, 10k and Doc discuss about the true nature of Lucy: will she be the salvation of mankind or will she contribute to destroy mankind? Murphy feels that they are talking about Lucy and he flees with her. But before he asks Cassandra to keep them in the spot. Meanwhile Warren sees Vasquez sneaking around and she follows him. He goes to the direction of a group of Zero that subdues him. Warren decides to help him but they are wounded by bullets and run to a derelict hospital. Meanwhile Addy, 10k and Doc plot to escape from Cassandra running to different directions. Will they succeed? What is the secret of Vasquez? Written by Claudio Carvalho, Rio de Janeiro, Brazil

Our Heroes try to cross the Mississippi but are involved in a boating accident and split up again. 10K is drawn into Sketchy and Skeezy's latest scam, resulting in a run in with Escorpion. Playing judge, jury and executioner all in one, Escorpion sentences 10K, Sketchy and Skeezy all to death. Warren and the rest of our Heroes arrive on the scene, but is it too late?

Tricked into a trap by use of a fresh brain lure, Murphy is captured by an overly enthusiastic and slightly unbalanced zombie fan, The Collector, who is hell-bent on adding him to his zombie museum. Murphy must match wits with the Collector if he's to survive, much less escape.

Mysterious things are starting to happen as our Heroes drive through RoZwell, New Mexico. Bright lights in the sky and the appearance of a beautiful but slightly 'spacey' woman, Bernadette, lead the team on an adventure through an abandoned Air Force base in search of zombie aliens. There they discover what looks like alien technology and quite possibly the answer to the question, Are we really alone in the universe?

Citizen Z warns that a horde of zombies is heading toward the survivors and they seek shelter. Doc and 10K stay behind since there is no vehicle for the whole group while Warren and Vasquez and Murphy and Addy drive two ATVs seeking for help. They reach a casino resort in the middle of the desert and they are helped by Chief Firecloud and his tribe. Meanwhile, Doc and 10K are captured by Firecloud's estranged son that blames the white men for the zombie virus. Will the survivors succeed to escape from the zombies? Written by Claudio Carvalho, Rio de Janeiro, Brazil

Our Heroes find themselves eyeball deep in corporate politics after they decide to seek shelter at a hotel taken over by a group of white collar survivors. While they're participating in trust falls and talking stick circles, someone tries to kill Murphy by shooting him. Suddenly faced with a possible killer in their midst, our Heroes play a dangerous game of Clue - with zombies!

Our Heroes are captured by the Zeros and taken to the Zero compound. There they are introduced to the Queen of the Zeros, La Reina. She tells them she is paving the way for a bold new future and instituting her own form of democracy via the Zeros. Impressed with our Heroes, La Reina invites them to join her team. Dr. Kurian is also at the Zero compound where he's been refining his Z-Vaccine and is finally ready for human trials. The first dose seems like a success and all the Zeros line up for their turn. Meanwhile Vasquez decides there's no time like the present to exact his revenge on Escorpion.

All hell breaks loose when it's discovered that Dr. Kurian's Z-Vaccine doesn't work at all! Instead of building an immunity to the Zombie Virus, the bad vaccine actually makes anyone inoculated susceptible to Murphy's unique brand of mind manipulation. Vasquez gets caught in his plot to kill Escorpion and is sentenced to death by La Reina. Murphy uses mental manipulation to position Warren as La Reina's new second in command. Warren frees Vasquez just in time to watch everyone who was inoculated succumb to a bizarre new form of the Zombie Virus.

Citizen Z finds that he has been hacked and recalls how he was invited to work in the Northern Light Post of NSA, after being arrested accused on espionage. Meanwhile the survivors reach California and now they are walking to get Murphy to the CDC. Warren recalls when she was a National Guard Lieutenant and found her soldiers turned into zombies. Doc recalls when he was at a mental institution to help addicted people when the outbreak busted. Addy was watching a hockey game and how she teamed-up with Mack to flee from the zombies. 10K was fishing in a river by the woods and he was saved by his father. Vasquez was at the funeral of his wife and daughter and soon the funeral director, his wife and his daughter turned into zombies. Murphy was in prison and witnessed inmates and guards turning into zombies. When they reach the location of CDC in accordance with the GPS, they find a restaurant with a woman behind bar counter. Written by Claudio Carvalho, Rio de Janeiro, Brazil

Los Angeles! Our Heroes drive through the abandoned city on their way to the coordinates of the mobile CDC lab given to them by Citizen Z. They head up towards Malibu where they discover the CDC lab isn't just a lab...it's a submarine! Dr. Merch welcomes our Heroes aboard and not a moment too soon as the Zeros show up hot on their heels. It's a bittersweet moment as Murphy says goodbye to the rest of our Heroes. As they leave Murphy and the fate of humanity with Dr. Merch, one question lingers; is this really the end of our grand adventure?