When a medical experiment turns into a blood-soaked nightmare, the only surviving subject flees for her life. Painfully missing her most precious memories of childhood, pummelled by horrific hallucinations, and pursued by those who stand to profit from her damaged brain, Amber Sheridan embarks on a cross-country road trip to track down a mysterious stranger – a man who has the ability to end Amber’s madness, and restore the memories that have been stolen from her.

In 1987, a group of film students go scout an abandoned resort in the Pennsylvania wilderness, becoming real victims in another film.