Invisible aliens in a tiny flying saucer come to Earth looking for heroin. They land on top of a New York apartment inhabited by a drug dealer and her female, androgynous, bisexual nymphomaniac lover, a fashion model. The aliens soon find the human pheromones created in the brain during orgasm preferable to heroin, and the model's casual sex partners begin to disappear.

Bored Roberta spots a regular personal ad in the paper titled 'Desperately Seeking Susan'. She heads off to New York, following one of the ads, and finds Susan. When Susan sells her jacket, Roberta - trying to emulate her mystery ad writer - buys the jacket and wears it. Little does she know someone is looking for the jacket - and its owner... Written by Colin Tinto cst@imdb.com