Jimmy Valentino has been saved by a miracle - or at least that's what he believes. Given his second chance, Jimmy conveys what he's discovered to other terminally ill patients who, to his astonishment, quickly recover. Jimmy tries to keep his profile and the results of his interventions under the radar but when word spreads, the world converges upon him. A few admire him. Some try to imitate him. Most denounce and disparage what he does as dangerous and sacrilegious. When a patient dies after following what he believes is Jimmy's advice, Jimmy is arrested and prosecuted. With his life in peril once again, Jimmy needs another miracle - one that can't be questioned.
A woman's one-night stand turns out to be her friend's husband, and a local political candidate.
Sammy Lagucci is a lovable loser who just wants to do right by his daughter. When he finds out the gangsters he runs with are planning to take him out, he enters the Witness Protection program to protect himself and his family. Going from The Big Apple to a small town in Wisconsin gets him down at first, but on a dare he does an impromptu stand-up comedy routine and finds he has a knack for it. His act goes viral, and what should be a blessing turns into a curse when his newfound fame gets the attention of the mob.