In a small Arctic town struggling with the highest suicide rate in North America, a group of Inuit students' lives are transformed when they are introduced to the sport of lacrosse.

A man who killed 13 years before goes out on the loose to kill his victims' children.

Claire tells the police officer, "It was all Jo's idea." But who's Jo? Jo is the bright spark in Claire’s recently darkened reality; a new friend in an otherwise isolated world. The two young women hit the town to let off some steam-and find themselves in trouble with local law enforcement. In the blink of an eye, Claire discovers that Jo is not what she seems-not at all-and her easy friendship with the lighthearted, young woman splits open to reveal the truth. Luminously shot in black and white, Josephine Doe is a raw exploration of family trauma and mental health that shows the thin line between our realities.