The film portrays Saint Peter reflecting on his time with Jesus and his fellow Apostles during his final imprisonment in Rome. In particular, Peter attempts to convert one of his jailers, Martinian, by relating the life, teachings, and sacrifice of Jesus.

Come Follow Me dramatizes the relationship between Jesus and the Apostle Peter. From the day Peter heard Jesus call his name to the post-resurrection conversation in which Jesus charges Peter to "feed my sheep," this short film beautifully illustrates Peter's transformation from fearful denier to the bold leader of the early church.