The theory of evolution and a re-write of American history are caught in the crosshairs when an unabashed Creationist seeks re-election as chairman of America's most influential Board of Education.

Bill Nye is retiring his kid show act in a bid to become more like his late professor, astronomer Carl Sagan. Sagan dreamed of launching a spacecraft that could revolutionize interplanetary exploration. Bill sets out to accomplish Sagan's mission, but he is pulled away when he is challenged by evolution and climate change contrarians to defend the scientific consensus. Can Bill show the world why science matters in a culture increasingly indifferent to evidence?