A suburban family struggles with the death of their 19 year-old son, following an overdose of heroin that was laced with fentanyl. The film explores the question of who and what is responsible for this tragedy.

Agnes is a woman who has reached her early 40s without ever venturing far from home, family or the tight-knit immigrant community in which she was raised by her widowed father. That begins to change in a quietly dramatic fashion when Agnes receives a jigsaw puzzle as a birthday gift and experiences the heady thrill of not only doing something she enjoys, but being very, very good at it.

Two teenagers from a remote religious community travel to town in search of shelter after being told by their Evangelical parents that an asteroid will soon destroy the earth.

An exhausted, workaholic actress, Anna Baskin, 44, abruptly extricates herself from a successful but mind-numbing TV role, returning to her past life in New York to reinvent herself. But despite the desire for transformation, she cannot find herself outside of her career. When an upsetting personal betrayal unexpectedly leads to the role of her life, she must confront the reality of her past relationships in order to clear a path forward. The intimate story of Anna and her friends Isaac and Kate become magnified by the film's surrounding themes: gentrification, addiction, autoimmune disease, burnout, sexism in the film industry and 21st century marketing of the self.