An astonishing fictional account of the unending series of murders of young women in Ciudad Juarez, Mexico, which began in 1996. Most of the victims are low-paid laborers who have been drawn to the town by the possibility of work at American-owned factories. In the film Mexican police officer Blanca Bravo is sent to Cuidad Juarez to investigate and comes to learn realities of these women's lives, as well as the truth about a police force and local power structure embodied by entrepreneur Mickey Santos that has ceased to care.

When her insurance company refuses to approve the care her husband needs to survive, Sonia Bonet (Jan Raluy) takes things into her own hands. Up against an unyielding bureaucracy and disinterested workers, she is pushed to her breaking point: with her son in tow, she attempts to fight the system.