While attempting to flee from the FBI, the criminal Frank Dallio kills Detective McKenna's wife, Rachel. McKenna himself is shot in the face by the professional killer Lyle Mason, who dies in a car crash shortly thereafter. The FBI persuades McKenna to undergo facial surgery and take the place of Lyle Mason in order to find Dallio and a valuable microchip.

RUSSELL MADNESS tells the story of Russell, an undersized but big-hearted terrier who dreams of having a family of his own. After running away from his pet store, Russell gets taken in by The Ferraros, a family desperate to revive their grandfather's pro wrestling arena. That's when they discover their new pet pooch has incredible wrestling skills. With help from his coach, Hunk, a savvy and hilarious monkey, Russell rockets to the top of the pro wrestling world and becomes a famous sports superstar. But when a dishonest promoter double-crosses the Ferraros, Russell will face his biggest challenge and discover that the strongest tag team is family.