A young girl is abducted by a man, who claims that a cult is hunting her. His goal is to protect her until sunrise but while restrained, the young girl falls deathly ill. While her friends and family search for her, the source of her illness becomes more and more apparent. She’s not sick…she’s changing.

During a late night taping of Dr. Nasty's Cavalcade of Horror, bloody chaos takes place while screening two features (Dinner for Monsters and Slit). Samantha/Nurse Nasty is frustrated with how the show is being run by its womanizing director and its drunk and crazy host, Dr. Nasty.