A road movie about a dysfunctional family who embark on a Lewis and Clark re-enactment trek and discover themselves and each other in the process.

Oscar and Peter land a career-making opportunity when a Chicago tycoon chooses them to compete for the design of a cultural center. The tycoon mistakenly believes that Oscar is gay and has him spy on his mistress Amy. Oscar goes along with it and ends up falling in love with Amy.

Dr. Richard Sturgess leads a team of compassionate doctors at a veteran's hospital. Along with Drs. Morgan, Handleman and Van Dorn, he fights to deliver adequate care to needy veterans in the face of funding cuts and a corrupt administration. To succeed, the staff may have to bend the rules and circumvent the villainous "Article 99," a bureaucratic loophole that prevents veterans from receiving the benefits they deserve.