When illness strikes two people who are polar opposites, life and death bring them together in surprising ways.

A former sorority girl, longing for her old, fun college days, decides to take a job as house mother to her former college chapter, only to find that it is in shambles. The handsome Dean of Student Affairs tells her she must turn the chapter around before the national organization yanks their charter and they will no longer be allowed on campus. As she works with the girls, she realizes she needs to be the grown up and help these young women discover their true potential. With the help of the Dean she comes up with a way to save the chapter and falls in love in the process.

High school sweethearts Maddie and Nate reconnect when Nate returns to their hometown to lecture at the hospital. Still hurt from their breakup, Maddie tries to avoid him. However, they eventually form a friendship, and Nate helps her as she secures funding to expand her cupcake shop. Just as Maddie and Nate rekindle their romance, Nate learns that a career opportunity awaits him in Boston. Devastated, Maddie returns the promise ring he gave her long ago and prepares for the grand reopening of her shop. Nate soon realizes how much he left behind, and must decide if his future lies in Boston with work or in his hometown with Maddie.