Takakura is a former detective. He receives a request from his ex-colleague, Nogami, to examine a missing family case that occurred 6 years earlier. Takakura follows Saki's memory. She is the only surviving family member from the case. Meanwhile, Takakura and his wife Yasuko recently moved into a new home. Their neighbor, Nishino, has a sick wife and a young teen daughter. One day, the daughter, Mio, tells him that the man is not her father and she doesn't know him at all.

In this seventh installment of the Ju-on franchise, a school teacher visits the home of a boy who's been absent from school for a long period of time, unaware of the horrific tragedy which occurred in the boy's household many years ago.

Following the events of Ju-on: The Beginning of the End, Mai, the older sister of elementary schoolteacher Yui Shono, goes to look for her sister, who disappeared after a year while working in an elementary school. Mai soon discovers the Teriyaki household who tells her about what happened to her sister. Mai will now uncover the dark secrets of Ju-on and will try to end the curse once and for all.