Detectives Sean and David Carter are on the case to find a gruesome serial killer terrorizing the city. Joining forces with Detective Christine Egerton, they dig deeper into a spiraling maze of horror that may not be of this world.

The plot of Children of the Corn: Runaway follows a young pregnant Ruth who escapes a murderous child cult in a small Midwestern town. She spends the next decade living anonymously in an attempt to spare her son the horrors that she experienced as a child. She lands in the small Oklahoma town, but something is following her. Now, she must confront this evil or lose her child.