Armed with an explosive powerful ancient cross amulet, Callan is back with his extraordinary team of weapons experts to defend Los Angeles from its biggest threat yet—super villains Muerte and Drago. Callan will have to join forces with his once mortal enemy, Gunnar, to try to save the city.

Callan (Brian Austin Green) returns to the scene with his team in order to oppose the return of the evil Gunnar (Vinnie Jones); his path crosses again with Frank Nitti (Tom Sizemore) detective under the city of Los Angeles.