Adah and Aaron are recovering addicts who are struggling to stay sober. After meeting in their psychoanalyst’s waiting room, they fall in love, relapse on poppers, and become the biggest assholes in New York City.

Creature of habit, Jon Smith, spends his days mindlessly working as a barista in New York City. When night falls, this seeming everyman savagely kills "filthy women" as his social outlet. A chance encounter with Delia, a young prostitute searching for an escape from her troubled past, forces Jon to confront the most terrifying thing he has ever faced in all his dark affairs - himself. All God's Creatures examines the true nature of what it means to be a monster and reveals that love is not only for a chosen few, but for all God's creatures.