Tchernobyl, 1986, a few hours before the disaster. Piotr and Anya's wedding is interrupted by a fire at the power station.

Oleg is a young gifted paramedic. His wife Katya works as a nurse at the hospital emergency department. She loves Oleg, but is fed up with him caring more about patients than her. She tells him she wants a divorce. The new head of Oleg’s EMA department is a cold-hearted manager who’s got new strict rules to implement. Oleg couldn’t care less about the rules – he’s got lives to save; his attitude gets him in trouble with the new boss. The crisis at work coincides with the personal life crisis. Caught up between their patients, alcohol-fueled off-shifts, and an evolving health care system, Oleg and Katya have to find the binding force that will keep them together.