In 1962 Yomama Bay the Japanese armed forces destroy yet another giant kaiju. Prof. Hiro Honda, rescues her offspring, whisking the mysterious red egg off to safety in friendly Cincinnati, Ohio. However, as the jet arrives, he accidentally flushes the egg down the toilet. It disappears into the Ohio River. Shaken loose by nuclear testing, the egg is quickly discovered by Dr. Blowheart and his assistant, Dr. Shirley Yujest. The two soon meet Prof. Honda, who tells them that the egg contains a living Notzillasaurus Partiontilldon. The creature will remain small, he explains, as long as it is not exposed to alcohol. But if it is, it will grow hundreds of times larger and attack the nearest city.

Ana Alvarez is a single mother from Nicaragua living in Northern Indiana with her teenage daughter, Izzy. When a routine check in leads to a deportation order, life as Ana knows it ends. The timing could not be worse as Izzy has just been accepted to Indiana University. Faced with an impossible reality of a lifetime away from her daughter, Ana decides to risk everything in a last chance effort to leave Izzy’s tuition paid before her time runs out.

Single mom Sarah moves into the suburbs and starts dating a firefighter, only to find herself the target of an obsessive neighborhood watchman who aims to prove he's the best man to protect her, even if he has to create the danger himself.