In the near future after a bitter civil war leaves Manhattan a demilitarized zone (DMZ), destroyed and isolated from the rest of the world, fierce medic Alma Ortega sets out on a harrowing journey to find the son she lost in the evacuation of New York City at the onset of the conflict. Standing in her way are gangs, militias, demagogues and warlords, including Parco Delgado, the popular — and deadly — leader of one of the most powerful gangs in the DMZ.

Four stylish and ambitious best girlfriends in Harlem, New York City: a rising star professor struggling to make space for her love life; a savvy tech entrepreneur always dating someone new; a no-filter singer; and a hopeless romantic fashion designer. Together, they level up into the next phase of their careers, relationships, and big city dreams.