In a world where mutated humans are treated with distrust and fear, an institute for mutants battles to achieve peaceful co-existence with humanity.

Private detective Cassie Dewell partners with ex-cop Jenny Hoyt on a search for two sisters who have been kidnapped by a truck driver on a remote highway in Montana. When they discover that these are not the only girls who have disappeared in the area, they must race against the clock to stop the killer before another woman is taken.