The series premieres with Zane Lamprey and his drinking buddies, Steve McKenna and Marc Ryan, visiting their first city on the Drinking Made Easy Tour, Phoenix, Arizona. Zane takes in a flight at Four Peaks Brewery, makes a monster prickly pear margarita at Aunt Chilada's and learns how to make illegal tequila. Meanwhile, Marc drinks dog beer at a Barkmitvah and Steve feeds his legend at Gilligan's Bar with 5lbs. of tater tots and a ranch dressing bomb. Written by Anonymous

Zane visits Santa Fe, New Mexico and mixes a $48 dollar margarita at Maria's New Mexican Kitchen, drinks a beer that can kill chickens at Santa Fe Brewing Company and eat some of the hottest chile pepper sauce in the state.

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Zane drinks his way through the Big Easy while suffering a brain freeze at Lafitte's Blacksmith Bar Shop, the oldest bar in the U.S.

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Zane Lamprey visits the City by the Bay. He meets with Fritz Maytag, who lead the craft beer revolution, drinks Fernet Branca upside down, and drinks on a mobile island.

Zane Lamprey visits San Diego. He drinks at Noble Experiment, a hidden speakeasy, drinks schooners or beer at the Shore Club, and hangs out with an Arrogant Bastard.