In 1876 Ernest Pratt, an imperfect man with vices, is a struggling writer of a series of books based on his popular and fictional character Nicodemus Legend. After being mistaken as Legend, Pratt is enlisted by a helpless group of town folk to once again help them, against a powerful female land owner and the town's sheriff in her pocket.

A well known bank robber name Jimmy Siringo comes to Pratt telling him he's been falsely accused of murdering a bank guard and stealing one million dollars, and wants his help in clearing his name of said charges.

A mystery man with a golden eye patch is threatening Pratt's life. At the same time Pratt also has to deal with problems from Custer.

Wild Bill Hickock seeks the help of Pratt's alter ego, Legend, but is turned down. But the bad still think they are working together, and both are now in peril.

Pratt recognizes a snakeoil salesman from back west, who has come to town spreading the word of the gospel, claiming to have changed.

Pratt and Bartok investigate the murder of a man who brought Bartok a dinosaur bone.

The European publisher branch of the Legend books, comes to town with his son, wanting to go on a great American hunt for buffalo, but his actions cause trouble with the Arapaho people.

Pratt is wrongfully convicted of murder and he, Bartok and Ramos must help clear his name.

The wife of the chief of the Black Foot Indians seeks Pratt's help in finding her parents, who she was separated from by accident when she was very young.

The skeleton of a dead Aztec indian leads Ramos on a journey to find out what happened to the stranger, and on a personal journey of his own.