Von Drake's Superhero Machine turns Dewey into supersmart, psychokinetic Brainboy, Louie into superstrong Captain Muscle and Huey into the Really Incredibly Fast Guy. But Donald is turned by mistake into supervillain, the Duck of Doom.

Mad scientist Horton Lautrec creates a devolution machine that can turn every living thing into their prehistoric ancestor and bring back the stone age. The machine turns Daisy's pet iguana, Knuckles, into a Godzilla-like giant lizard.

Daisy is sent to do a report on Quintinia, a modern day medieval kingdom, and Donald drives her there. The locals recognize Donald and declare him their long lost king. Evil prince Gaylord tries to assassinate Donald and take the throne.

Donald's been discharged from the navy a day too early, so he returns to serve out one more day on an aircraft carrier. When his dogfighting video game takes over the ship and starts war games, only Donald's gaming skills can stop it.

The fourth Columbo's ship called Snooky holds the priceless jeweled key of Carpathia and only Daisy and her TV crew can see it. Master thief Nigel Nightshade tries to trick her cameraman Donald and get the key. The nephews recognize him.

Daisy interviews egotistical car racing champ, the Rocket. He hits on her, so jealous Donald decides to race against him. The nephews even get him some of Von Drake's potent rocket fuel, but things don't go as planned.

Mad lab assistant Tovar, who loves germs and wants to save them from medicine, uses his invention, the Germinator, to miniaturize himself and help the germs take over Donald's body. The nephews miniaturize themselves and go after Tovar.

In order to justify being late for work again, Donald comes up with an epic tale of heroism that includes mail delivery, outsmarting a dinosaur and even an alien invasion. And it all happened to him that very morning.

Donald's nephews discover incredibly tasty and addictive green goo and become filthy rich overnight by selling it as food. Greed, apathy and egotism quickly consume them. But then, the goo turns into a giant, rampaging monster.

The nephews send the tapes of Donald being the butt of their pranks to the Funniest Home Videos and he becomes an overnight sensation. The sleazy producers decide to raise the stakes by putting gullible Donald in real danger.

The elephant-looking aliens from The Late Donald Duck return seeking vengeance against Donald. The nephews use the Superhero Machine from The Really Mighty Ducks to regain their powers and try to save him.

While Donald and his nephews are fishing on the river, Daisy goes to see a nearby castle. She meets a strange, slightly unhinged, yet well-meaning nobleman called Gil, who's obsessed with making his depressed giant pet koi fish happy.

While recklessly playing his nephews' fun virtual reality game, Donald ends up wrecking both it and his apartment. He cowardly blames it on a thief he made up. Dangerous criminal, Claw, who happens to match his description, seeks revenge.

Daisy takes Donald and the nephews to the desert to investigate a secret science facility run by Dr. Emil who found a way to recombine molecules and has a bone to pick with Daisy. Meanwhile, the nephews' sibling rivalry escalates.

Huey wants to enter a cool teen contest, so wants to look his very best. But when he goes to the dentist to get his teeth whitened, he's outfitted with what he believes to be braces, but it is in reality a special mind-control device intended for someone else and the mastermind will stop at nothing to get it back. Written by adventure