HankMed turns a new page after Boris buys Hamptons Heritage. Hank loses Charlotte and takes on the case of TV host who is hosting a party at the Newberg house. Evan and Paige discover that they may be having a baby.

Hank treats a triathlon patient who also gives him some dating advice. Even is worried that he may already be a father. Jeremiah helps clear Divya's name, but her arrest video goes viral.

An intense Hollywood method actor wants to shadow Hank to prepare for his next role. Meanwhile, Divya performs a genetic test on a royal patient who doesn't want to play by the rules.

Hank treats a transgender teenager and learns her life is more complicated than he expected. Evan and Jeremiah host a gala fundraiser for the Center for Rare and Orphan Diseases and Jeremiah makes a major purchase for the lab. Meanwhile Paige and Evan's journey to parenthood takes an unexpected turn, and Divya grows closer to Prince Quami.

Hank goes to Manhattan with Olympia, but their time away together isn't exactly what he expected. Evan fears Boris is keeping a secret from him within the hospital, and a surprise visitor from her past leads Divya to feel overwhelmed by the men in her life. Paige is eager for her home renovations to be finished and is shocked when she discovers the reason for the delay.

Boris is forced to share his secret plans with Evan. Divya deals with what appears to be a Smallpox outbreak. A patient sets Hank up on a double date. Jeremiah lays low after his big business mistake.

Hank helps Boris prep a secret patient for surgery as Evan tries to chase a bad omen out of the hospital. An offer from Quami leads Divya to make a major decision about her personal life.

Evan and Paige's surrogate daughter goes into labor, Hank runs into his ex-fiancée from New York and discovers unresolved issues with her, and Divya prepares for big life changes after her grandmother dies.