In Ashe County, deputies go on a rugged mountain manhunt in search of a fugitive wanted for assault and resisting arrest. After harming his girlfriend, he needs to be caught before he hurts someone else ... or himself. In Sullivan County, it's one of those weeks. Deputy Gilliam responds to an accident scene after a driver crashes her car through the front window of a chiropractor's office.

In Sullivan County, Tennessee, they don't call Deputy Travis Jackson Action Jackson for no reason. When he is assigned to serve a warrant on a hard-to-find fugitive, he gets creative. So when Brandon Lane, wanted for assault, gets on Jackson's hit list, he has no idea what's coming. Jackson takes advantage of Lane's girlfriend having a lost dog to find himself a lost fugitive.

Deputies in Sullivan County, Tennessee, and Ashe County, North Carolina, know their populations increase during the fall because it's deer-hunting season. With more people come more guns and complex issues involving the legal use of firearms. In addition to hunting down drug dealers, DUI offenders and wanted criminals, officers need to hunt down hunters who may not be following the law.

A knife fight breaks out between two migrant workers harvesting Christmas trees in Ashe County. Deputies also receive a 911 call from an elderly woman who claims her troublesome nephew is harassing her. Sullivan County deputies conduct a manhunt for one of the county's most-wanted fugitives while also trying to solve the mystery of a torched stolen car.

Deputies track a couple on Sullivan County, Tennessee�۪s most wanted list. They�۪ve been on the lam for a year for an alleged string of burglaries, and there are plenty of places for them to hide. In Ashe County, North Carolina, a man with dementia is caught in the middle of a domestic battle and a deputy needs to be both officer and psychologist to resolve the chaotic situation.

Deputies in Sullivan County apprehend drug dealers they've been tracking for months. Ashe County deputies bust the ringleaders of a major meth lab.

Nearly 80 percent of the inmates in Sullivan and Ashe County jails are incarcerated for some offense related to drugs and alcohol. People having sex in a driveway, an intoxicated man screaming on the floor of a jail cell and an addicted couple on the run illustrate the challenges deputies in these counties face every day trying to keep the area's addiction issues under control.