The medicine required for Spock, who has contracted a fatal disease, is stolen by Orion pirates.

The Enterprise crew is being observed as their suitability to meet with advanced civilizations.

In the midst of a stand-off with the Rimulans, The Enterprise's computer systems, gain partial sentience, and with it, starts playing practical jokes upon the crew, which leads to a dangerous life-and-death battle with Romulans. Written by Tony-B4

Dr. McCoy is arrested and charged with causing an alien plague.

The Enterprise runs into a being which once visited Earth, and influenced the Mayan culture.

The Enterprise is transporting its first Captain, Robert April to Babel, where he will reluctantly accept his retirement. When the Enterprise attempt to stop an unidentified vessel on a collision course with the Beta Niobe nova, the ship accidentally pass into an alternate dimension, where time flows in the opposite direction. The crew of the Enterprise rapidly begins to grow younger in age, and soon become unable to man the consoles. Written by The TV Archaeologist