In a world where superheroes have been real for decades, an accountant with no superpowers comes to realize his city is owned by a super villain. As he struggles to uncover this conspiracy, he falls in league with a strange blue superhero.

The Tick, a clueless but well-intentioned superhero pursues the ultimate evil enemy, The Terror with the help of his reluctant sidekick.

Tick and Arthur have a run-in with local villainess Miss Lint and her gang, who will stop at nothing to get back the mysterious super-suit that Tick took from them and gave to Arthur. Dot, Arthur's paramedic sister, moonlights for an unsavory business.

Arthur takes a break from hunting the Terror and tries to get back to his safe, normal, and unheroic life as an accountant unaware he's being stalked by the menacing vigilante Overkill. Tick confesses to an existential crisis.

Tick crashes an Everest family party to convince Arthur's sister Dot of her brother's super-heroic destiny. Another more dangerous party-crasher arrives to threaten Arthur and his family.

Tick and Dot help Arthur try to control his flyaway super-suit as the Pyramid Gang pursues them. Miss Lint has an unexpected caller.

Tick and Arthur try to use Ramses to prove that the Terror is alive and run into trouble. Miss Lint takes the advice of an old friend.

Arthur has a surprising encounter while in The Terror's lair. The Tick attempts a rescue with Dot and Overkill.

Arthur, Dot, and Overkill try to get a message to Superian, with the help of a retired hero.

The Tick and Arthur rush to rescue the endangered Dr. Karamazov. Dot gets some personal information from Overkill.

The Tick and Arthur harbor an out of commission Superian. Dot gathers more intel on the Pyramid Gang, and Overkill confronts Miss Lint.

The team races to counteract The Terror's plan for Big Bismuth and the VLM. Miss Lint and Overkill have something resembling a heart to heart.

The Tick and Arthur find themselves on a final collision course with The Terror as he attempts to bring his evil plans to fruition.