Trapper John and Gonzo are captured while at their vineyard. A representative for survivors of nuclear radiation exposure tries to get help from San Francisco Memorial.

Jackpot recommends surgery for a man who suffers from Munchausen syndrome, a psychological disorder which leads him to fake symptoms.

A miserly industrialist with an obsession for anonymity badgers the hospital staff.

On a foggy Thanksgiving, Slocum hits Trapper with his car. As John fights for his life, staff members recall (in flashbacks) reasons they have to be thankful for his friendship and help.

Gonzo and Shoop send Trapper on vacation to Geneva Springs. While Trapper substitutes for a small-town doctor, Riverside is fired and a former patient of Trapper's needs heart surgery.

Talented neurosurgeon Russ Brandis enduring a deadly disease and fits of rage he shows are due to the drugs he must take. The surgeon's personal problems are uncovered as Riverside and Gonzo try to recruit him for the hospital staff.

Vinnie Duncan, Gonzo's good friend, leads a fund campaign for rare-disease drugs.

A baby admitted to the hospital for a urinary tract infection turns out to be a hermaphrodite, sparking a battle between the parents over which sex it should be.

When Gloria Brancusi learns that Andrea, the orphan girl, has come back to the hospital as a patient her first reaction is to run away. Gloria has second thoughts after deciding to adopt the troubled orphan.

A brilliant surgeon begins suffering from bouts of forgetful and disoriented behavior.

Gonzo's mother introduces him to her new boyfriend, a sportswriter his age. Gonzo is not happy about the situation.

When Gonzo starts dating a high society woman she tries to convince set up his own private practice and into selling the "Titanic" to Jackpot.